Clinical Informatics for Precision Cancer Medicine: Computational Methods for Interpreting Individual Whole Exome and Transcriptome Tumor Sequence Data.
Nathanael D. MooreBrendan ReardonEliezer M. Van AllenPublished in: AMIA (2017)
Keyphrases
- computational methods
- sequence data
- breast cancer
- alternative splicing
- disease progression
- cancer treatment
- cancer patients
- cancer diagnosis
- computational approaches
- tissue samples
- profile hidden markov models
- statistical methods
- normal tissue
- treatment planning
- sequence similarity
- prostate cancer
- cancer cells
- lung cancer
- data mining
- high precision
- clinical trials
- secondary structure
- biological sequences
- copy number
- binding sites
- protein protein interactions
- statistical analysis
- data sources
- feature selection