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High-throughput virtual screening and preclinical analysis identifies CB-1, a novel potent dual B-Raf/c-Raf inhibitor, effective against wild and mutant variants of B-Raf expression in colorectal carcinoma.

Mesfer Al ShahraniMohammad AbohassanMohammad Y. AlshahraniAbdulrahim R. HakamiPrasanna Rajagopalan
Published in: J. Comput. Aided Mol. Des. (2021)
Keyphrases
  • high throughput
  • virtual screening
  • genome wide
  • systems biology
  • microarray
  • biological data
  • data acquisition
  • query processing
  • dimensionality reduction
  • drug discovery