Language models enable zero-shot prediction of the effects of mutations on protein function.
Joshua MeierRoshan RaoRobert VerkuilJason LiuTom SercuAlexander RivesPublished in: NeurIPS (2021)
Keyphrases
- language model
- protein function
- protein function prediction
- language modeling
- probabilistic model
- n gram
- query expansion
- protein interaction
- information retrieval
- retrieval model
- protein sequences
- protein structure prediction
- statistical language models
- computational methods
- smoothing methods
- protein interaction networks
- protein protein interactions
- gene ontology
- amino acids
- functional modules
- language models for information retrieval
- relevance model
- computational biology
- graph theory
- protein structure
- multi label
- social network analysis
- knowledge discovery
- high dimensional