CRISPRpred(SEQ): a sequence-based method for sgRNA on target activity prediction using traditional machine learning.
Ali Haisam Muhammad RafidMd. ToufikuzzamanMohammad Saifur RahmanM. Sohel RahmanPublished in: BMC Bioinform. (2020)
Keyphrases
- machine learning
- cost function
- high accuracy
- machine learning methods
- natural language processing
- preprocessing
- high precision
- significant improvement
- objective function
- prediction model
- experimental evaluation
- computational cost
- support vector machine svm
- pattern recognition
- computer vision
- dynamic programming
- prior knowledge
- artificial neural networks
- pairwise
- prediction algorithm
- classification method
- synthetic data
- data sets
- detection algorithm
- unsupervised learning
- input data
- markov random field
- support vector machine
- probabilistic model
- computational complexity