Evolutionarily Conserved Substrate Substructures for Automated Annotation of Enzyme Superfamilies.
Ranyee A. ChiangAndrej SaliPatricia C. BabbittPublished in: PLoS Comput. Biol. (2008)
Keyphrases
- protein sequences
- protein families
- sequence alignment
- amino acids
- comparative genomics
- multiple sequence alignments
- structural motifs
- substructure discovery
- computational biology
- protein structure
- secondary structure
- data structure
- graph mining
- magnetic recording
- phylogenetic analysis
- rna structures
- heat flow
- protein folding
- semiconductor devices
- metabolic pathways
- multiple sequence alignment
- protein structure prediction
- graph databases
- structured data
- pairwise
- structural patterns
- data sets
- computer simulation
- genetic algorithm