Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression.
Matt SilverEva JanousováXue HuaPaul M. ThompsonGiovanni MontanaPublished in: NeuroImage (2012)
Keyphrases
- gene expression
- sparse regression
- expression profiles
- complex diseases
- signaling pathways
- differential expression
- microarray
- related genes
- biological entities
- gene expression profiles
- feature selection and classification
- gene clusters
- single nucleotide polymorphisms
- microarray data
- biological knowledge
- biological processes
- genetic variation
- protein protein interaction networks
- gene expression data
- gene ontology
- cell cycle
- image processing
- gene sets
- low rank
- high throughput
- biological networks
- biomedical literature
- genome wide
- systems biology
- gene expression analysis
- breast cancer
- gene regulatory networks
- variable selection
- biological data
- medical imaging
- gene selection
- sequence data
- genome wide association studies
- protein protein interactions
- functional modules
- human genome
- microarray datasets
- gene networks