Multifactor dimensionality reduction for graphics processing units enables genome-wide testing of epistasis in sporadic ALS.
Casey S. GreeneNicholas A. Sinnott-ArmstrongDaniel S. HimmelsteinPaul J. ParkJason H. MooreBrent T. HarrisPublished in: Bioinform. (2010)
Keyphrases
- genome wide
- dimensionality reduction
- gene gene interactions
- graphics processing units
- high throughput
- complex diseases
- general purpose
- genome wide association studies
- gpu implementation
- high dimensional data
- human genome
- high dimensional
- parallel processing
- transcription factors
- feature extraction
- feature space
- high dimensionality
- decision trees
- parallel implementation
- floating point
- principal component analysis
- low dimensional
- biological data
- parallel computing
- high performance computing
- pairwise
- feature selection
- single nucleotide polymorphisms
- data points
- computing systems
- real time