Finding trans-regulatory genes and protein complexes modulating meiotic recombination hotspots of human, mouse and yeast.
Min WuChee Keong KwohXiaoli LiJie ZhengPublished in: BMC Syst. Biol. (2014)
Keyphrases
- protein complexes
- protein interaction
- saccharomyces cerevisiae
- protein interaction data
- biological processes
- protein protein interactions
- protein protein interaction networks
- gene expression
- protein interaction networks
- gene ontology
- genomic data
- gene regulation
- transcription factors
- functional modules
- gene expression data
- microarray
- cellular processes
- signaling pathways
- interacting proteins
- dna binding
- protein function
- biomedical literature
- biological data
- systems biology
- ppi networks
- computational methods
- high throughput
- computational approaches
- high throughput experimental
- cell cycle
- interaction networks
- regulatory networks
- biological systems
- microarray data
- computational biology
- genome scale
- expression profiles
- binding sites
- gene regulatory networks
- biological networks
- computational tools
- network topology
- information flow
- dna sequences
- experimental conditions
- machine learning
- component analysis