Computational molecular perspectives on novel carbazole derivative as an anti-cancer molecule against CDK1 of breast and colorectal cancers via gene expression studies, novel two-way docking strategies, molecular mechanics and dynamics.
Eashita SuvarnaAnagha S. SetlurChandrashekar KSridharan MVidya NiranjanPublished in: Comput. Biol. Chem. (2024)
Keyphrases
- gene expression
- gene expression profiles
- gene selection
- functional genomics
- drug discovery
- microarray
- gene expression data
- drug design
- meta analysis
- cancer diagnosis
- microarray data
- dna microarray
- colon cancer
- cancer classification
- cancer treatment
- gene expression data analysis
- ovarian cancer
- high throughput technologies
- breast cancer
- survival prediction
- gene expression patterns
- high throughput
- biological processes
- microarray datasets
- gene regulation
- transcriptional regulation
- lung cancer
- interaction networks
- microarray technology
- gene expression data sets
- systems biology
- biological networks
- analysis of gene expression
- gene ontology
- expression profiles
- differentially expressed genes
- gene interactions
- signaling pathways
- gene networks
- tissue samples
- binding sites
- high dimensional
- gene sets
- genomic data
- regulatory networks
- high dimensionality
- transcription factors
- prostate cancer
- gene expression microarray data