AutoPH4: An Automated Method for Generating Pharmacophore Models from Protein Binding Pockets.
Siduo JiangMiklos FeherChristopher I. WilliamsBrian ColeDavid E. ShawPublished in: J. Chem. Inf. Model. (2020)
Keyphrases
- probabilistic model
- fully automatic
- statistical methods
- high accuracy
- clustering method
- linear model
- highly accurate
- linear regression
- cost function
- significant improvement
- model selection
- parameter estimation
- objective function
- detection method
- machine learning methods
- bayesian framework
- prior knowledge
- pairwise
- computational methods
- computational complexity