Exploring the Composition of Protein-Ligand Binding Sites on a Large Scale.
Nickolay A. KhazanovHeather A. CarlsonPublished in: PLoS Comput. Biol. (2013)
Keyphrases
- binding sites
- protein protein
- virtual screening
- dna binding
- sequence alignment
- protein protein interactions
- sequence data
- gene expression
- regulatory elements
- dna sequences
- transcription factors
- drosophila melanogaster
- protein interaction
- high throughput
- computational methods
- biological sequences
- protein sequences
- protein structure
- transcription factor binding sites
- protein families
- motif discovery
- statistical significance
- predicting protein
- interaction networks
- influenza virus
- genome wide
- genome sequences
- microarray
- drug design
- network topology
- molecular biology
- amino acid sequences
- protein function
- regulatory networks
- cis regulatory
- high precision