Mining high-throughput screens for cancer drug targets - lessons from yeast chemical-genomic profiling and synthetic lethality.
Marja A. HeiskanenTero AittokallioPublished in: WIREs Data Mining Knowl. Discov. (2012)
Keyphrases
- high throughput
- drug discovery
- systems biology
- virtual screening
- microarray
- genome wide
- biological data
- genomic data
- protein protein interactions
- microarray technology
- analysis of gene expression
- gene selection
- gene expression levels
- proteomic data
- data acquisition
- data mining
- gene expression profiles
- protein protein
- dna microarray
- pattern mining
- gene expression
- drug design
- biological processes
- mass spectrometry
- cancer diagnosis
- interaction networks
- mass spectrometry data
- gene expression data
- knowledge discovery
- cell cycle
- cancer classification
- transcription factors
- microarray data