Using the drug-protein interactome to identify anti-ageing compounds for humans.
Matías FuentealbaHandan Melike DönertasRhianna WilliamsJohnathan LabbadiaJanet M. ThorntonLinda PartridgePublished in: PLoS Comput. Biol. (2019)
Keyphrases
- drug discovery
- pharmaceutical industry
- chemical compounds
- virtual screening
- protein protein interactions
- drug design
- protein interaction
- early stage
- systems biology
- subcellular localization
- scientific data
- experimental data
- discovery process
- physico chemical
- amino acid sequences
- protein function
- data mining tools
- biological systems
- protein structure
- protein sequences
- high throughput