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Insights to the Binding of a Selective Adenosine A3 Receptor Antagonist Using Molecular Dynamic Simulations, MM-PBSA and MM-GBSA Free Energy Calculations, and Mutagenesis.

Panagiotis LagariasKerry BarkanEva TzortziniMargarita StampelouEleni VrontakiGraham LaddsAntonios Kolocouris
Published in: J. Chem. Inf. Model. (2019)
Keyphrases
  • free energy
  • three dimensional
  • upper bound
  • computational methods
  • drug discovery
  • neural network
  • computer vision
  • higher order
  • maximum likelihood