The cis-trans binding strength defined by motif frequencies facilitates statistical inference of transcriptional regulation.
Yance FengSheng ZhangLiang LiLei M. LiPublished in: BMC Bioinform. (2019)
Keyphrases
- statistical inference
- transcription factors
- transcriptional regulation
- binding sites
- statistical learning
- graphical models
- model selection
- bayesian inference
- dna binding
- statistical methods
- genome wide
- component analysis
- transcription factor binding sites
- microarray
- dna sequences
- machine learning
- high throughput
- regulatory elements
- motif discovery
- systems biology
- information retrieval
- training set
- information extraction
- computational biology
- unsupervised learning