A phylogenetic and Markov model approach for the reconstruction of mutational pathways of drug resistance.
Patricia BuendiaBrice CadwalladerVictor DeGruttolaPublished in: Bioinform. (2009)
Keyphrases
- drug resistance
- markov model
- markov chain
- human immunodeficiency virus
- statistical model
- image reconstruction
- three dimensional
- hidden markov models
- temporal sequences
- hiv protease
- dynamic programming
- markov networks
- probability distribution
- maximum likelihood
- learning algorithm
- pairwise
- phylogenetic trees
- bayesian networks