Estimation of total mediation effect for high-dimensional omics mediators.
Tianzhong YangJingbo NiuHan ChenPeng WeiPublished in: BMC Bioinform. (2021)
Keyphrases
- high dimensional
- low dimensional
- similarity search
- data sources
- data sets
- estimation problems
- accurate estimation
- sparse data
- high dimensionality
- multi dimensional
- multi agent
- parameter estimation
- high dimensional data
- generalized linear models
- database
- variable selection
- gene expression data
- machine learning
- genetic algorithm
- dimensionality reduction
- data points
- model selection
- nearest neighbor
- data quality
- knn
- estimation algorithm
- maximum likelihood estimation
- information systems
- case study
- high dimensional problems
- feature space