Exploring the effectiveness of the TSR-based protein 3-D structural comparison method for protein clustering, and structural motif identification and discovery of protein kinases, hydrolases, and SARS-CoV-2's protein via the application of amino acid grouping.
Titli SarkarVijay V. RaghavanFeng ChenAndrew RileySophia ZhouWu XuPublished in: Comput. Biol. Chem. (2021)
Keyphrases
- amino acids
- protein sequences
- protein structure
- contact map
- contact maps
- protein structural
- protein function
- protein structure prediction
- psi blast
- protein folding
- sequence alignment
- experimentally determined
- amino acid sequences
- clustering method
- physico chemical
- mass spectrometry
- sequence analysis
- computational biology
- tertiary structure
- secondary structure
- dynamic programming
- high precision
- protein interaction
- structural motifs
- protein secondary structure prediction
- protein protein interactions
- machine learning
- protein protein
- protein classification
- physicochemical properties
- computational methods
- pairwise