Reliable prediction of protein thermostability change upon double mutation from amino acid sequence.
Liang-Tsung HuangM. Michael GromihaPublished in: Bioinform. (2009)
Keyphrases
- contact maps
- amino acid sequences
- protein tertiary structure
- protein structure prediction
- contact map
- protein structure
- tertiary structure
- protein secondary structure
- protein sequences
- amino acids
- predicting protein
- secondary structure
- protein chains
- physico chemical
- protein secondary structure prediction
- molecular biology
- coarse grained
- secondary structure prediction
- protein function
- physicochemical properties
- fine grained
- sequence analysis
- drug design
- computational biology
- prediction accuracy
- protein classification
- disordered regions
- protein folding
- protein interaction
- graph theory
- secondary structure of proteins
- psi blast
- sequence alignment
- sequence data
- solvent accessibility
- computational methods
- data analysis