In Silico Footprinting of Ligands Binding to the Minor Groove of DNA.
Nahoum G. AnthonyGuillaume HuchetBlair F. JohnstonJohn A. ParkinsonColin J. SucklingRoger D. WaighSimon P. MackayPublished in: J. Chem. Inf. Model. (2005)
Keyphrases
- transcriptional regulation
- transcription factor binding sites
- biological data
- saccharomyces cerevisiae
- gene regulatory networks
- binding sites
- high throughput
- virtual screening
- dna sequences
- gene expression
- transcription factors
- computational methods
- genome wide
- microarray data
- microarray
- cis regulatory
- computer simulation
- systems biology
- dna binding
- molecular biology
- biological sequences
- regulatory networks
- network model
- drug design
- dna computing
- gene expression data
- reverse engineering
- gene regulation
- interaction networks
- signaling pathways
- data analysis
- biological networks
- statistical significance
- motif discovery
- machine learning
- dynamic bayesian networks
- biological processes
- component analysis
- data sources
- statistical methods
- sequence data
- regulatory elements
- data integration