CRF-based models of protein surfaces improve protein-protein interaction site predictions.
Zhijie DongKeyu WangTruong Khanh Linh DangMehmet GültasMarlon WelterTorsten WierschinMario StankeStephan WaackPublished in: BMC Bioinform. (2014)
Keyphrases
- protein protein interactions
- predicting protein
- computational methods
- conditional random fields
- statistical models
- protein interaction data
- pairwise
- high precision
- high throughput
- predicting protein protein interactions
- protein protein
- protein interaction
- biological processes
- protein function
- drug design
- biomedical literature
- gene ontology
- cellular processes
- genomic data
- functional modules
- protein complexes
- signaling pathways
- protein structure
- feature selection