Understanding Variation in Transcription Factor Binding by Modeling Transcription Factor Genome-Epigenome Interactions.
Chieh-Chun ChenShu XiaoDan XieXiaoyi CaoChun-Xiao SongTing WangChuan HeSheng ZhongPublished in: PLoS Comput. Biol. (2013)
Keyphrases
- dna binding
- transcription factors
- transcriptional regulation
- binding sites
- cis regulatory
- microarray
- component analysis
- gene expression
- genome wide
- dna sequences
- computational biology
- regulatory networks
- chip seq
- systems biology
- transcriptional regulatory
- sequence data
- gene regulation
- human genome
- genome sequences
- transcription factor binding sites
- regulatory elements
- biological processes
- motif discovery
- high throughput
- saccharomyces cerevisiae
- biomedical literature
- highly correlated
- co occurrence
- gene sets
- social networks
- computational methods
- gene expression levels
- statistically significant
- statistical significance