Nicotine Enantioselectively Targets Myeloid Differentiation Protein 2 and Inhibits the Toll-like Receptor 4 Signaling.
Pu JiangCong ZhangHongshuang WangPenghui LiXiubo DuYibo WangEkaterina LyukmanovaCong LinXiaohui WangPublished in: J. Chem. Inf. Model. (2024)
Keyphrases
- drug discovery
- protein structure
- protein sequences
- signaling pathways
- amino acids
- subcellular localization
- protein structure prediction
- dead end
- protein function
- target detection
- multiple targets
- influenza virus
- virtual screening
- chemical compounds
- target tracking
- mass spectra
- tandem mass spectra
- sequence alignment
- moving target
- contact map
- drug design
- protein protein interactions
- protein folding
- mass spectrometry
- molecular dynamics
- dna binding
- protein protein interaction networks
- biological systems
- early stage