Landscape-Based Protein Stability Analysis and Network Modeling of Multiple Conformational States of the SARS-CoV-2 Spike D614G Mutant: Conformational Plasticity and Frustration-Induced Allostery as Energetic Drivers of Highly Transmissible Spike Variants.
Gennady M. VerkhivkerSteve AgajanianRyan KassabKeerthi KrishnanPublished in: J. Chem. Inf. Model. (2022)
Keyphrases
- stability analysis
- protein folding
- spiking neurons
- neuronal networks
- spike trains
- experimentally determined
- nonlinear systems
- synaptic weights
- spiking neural networks
- coarse grained
- amino acids
- protein structure
- wireless sensor networks
- feed forward
- protein complexes
- hiv protease
- adaptive control
- real time
- input patterns
- state space
- expert systems
- reinforcement learning
- artificial intelligence
- neural network