An algorithm for the determination and quantification of components of nucleic acid mixtures based on single sequencing reactions.
Alexander E. PozhitkovKathryn StemshornDiethard TautzPublished in: BMC Bioinform. (2005)
Keyphrases
- cost function
- optimal solution
- times faster
- worst case
- expectation maximization
- learning algorithm
- preprocessing
- detection algorithm
- optimization algorithm
- computational cost
- np hard
- significant improvement
- convergence rate
- estimation algorithm
- matching algorithm
- mixtures of gaussians
- simulated annealing
- em algorithm
- high accuracy
- dynamic programming
- search space
- objective function
- computationally efficient
- ant colony optimization
- k means
- recognition algorithm
- gaussian mixture
- computational complexity