Amino acid variants of SARS-CoV-2 papain-like protease have impact on drug binding.
Agata P. PerlinskaAdam StasiulewiczMai Lan NguyenKarolina SwiderskaMikolaj ZmudzinskiAlicja W. MaksymiukMarcin DragJoanna I. SulkowskaPublished in: PLoS Comput. Biol. (2022)
Keyphrases
- amino acids
- physico chemical
- drug design
- protein structure prediction
- protein sequences
- hiv protease
- secondary structure
- protein folding
- drug resistance
- protein structure
- sequence alignment
- amino acid sequences
- protein function
- quantitative structure activity
- human immunodeficiency virus
- coarse grained
- drug discovery
- data mining
- public health
- graph theory
- tertiary structure
- machine learning