Insights into changes in binding affinity caused by disease mutations in protein-protein complexes.
Sherlyn JemimahM. Michael GromihaPublished in: Comput. Biol. Medicine (2020)
Keyphrases
- protein complexes
- protein protein interaction networks
- molecular level
- protein interaction data
- protein protein interactions
- protein interaction networks
- protein interaction
- protein function
- functional modules
- computational approaches
- cellular processes
- protein protein
- genomic data
- saccharomyces cerevisiae
- protein functional
- essential proteins
- computational biology
- hiv protease
- biological processes
- computational methods
- ppi networks
- biological knowledge
- predicting protein
- biological networks
- network topology
- data mining
- complex networks
- protein sequences
- interaction networks
- signaling pathways
- high throughput
- gene expression
- network analysis
- data analysis
- biological data