Improving protein-ligand binding site prediction accuracy by classification of inner pocket points using local features.
Radoslav KrivákDavid HokszaPublished in: J. Cheminformatics (2015)
Keyphrases
- prediction accuracy
- predictive power
- predictive accuracy
- protein protein
- binding sites
- classification accuracy
- virtual screening
- feature set
- feature space
- improve the prediction accuracy
- benchmark datasets
- ensemble methods
- computational methods
- protein protein interactions
- protein families
- dna binding
- drug discovery
- decision trees
- statistical analysis
- feature selection
- high dimensionality
- high throughput
- roc curve
- protein structure
- drug design
- protein sequences
- regulatory elements
- web page prediction