Inference of Genome-Scale Gene Regulatory Networks: Are There Differences in Biological and Clinical Validations?
Frank Emmert-StreibMatthias DehmerPublished in: Mach. Learn. Knowl. Extr. (2019)
Keyphrases
- gene regulatory networks
- genome scale
- saccharomyces cerevisiae
- systems biology
- dynamic bayesian networks
- bayesian inference
- regulatory networks
- metabolic pathways
- biological data
- gene expression data
- network model
- gene regulation
- reverse engineering
- gene networks
- interaction networks
- high throughput
- biological processes
- cell cycle
- structure learning
- bayesian networks
- protein protein interaction networks
- microarray data
- molecular biology
- biological systems
- protein protein interactions
- graphical models
- biological knowledge
- approximate inference
- biological networks
- probabilistic inference
- particle filtering
- probabilistic model
- genomic data
- high dimensionality
- belief propagation
- microarray
- feature space
- feature selection