Identifying essential proteins via integration of protein interaction and gene expression data.
Xiwei TangJianxin WangYi PanPublished in: BIBM (2012)
Keyphrases
- gene expression data
- protein interaction data
- protein interaction
- gene expression
- protein interaction networks
- protein protein interactions
- microarray
- protein complexes
- regulatory networks
- gene regulatory networks
- genomic data
- microarray data
- high throughput
- functional modules
- gene ontology
- high dimensionality
- feature selection
- protein function
- binding sites
- data sets
- gene expression profiles
- computational methods
- saccharomyces cerevisiae
- high dimensional data
- biological processes
- biological networks
- data integration
- high dimensional
- systems biology
- drug design
- structural properties