A graphical model approach visualizes regulatory relationships between genome-wide transcription factor binding profiles.
Felicia S. L. NgDavid RuauLorenz WernischBerthold GöttgensPublished in: Briefings Bioinform. (2018)
Keyphrases
- graphical models
- genome wide
- transcription factors
- dna binding
- chip seq
- high throughput
- belief propagation
- transcriptional regulation
- cis regulatory
- transcription factor binding sites
- probabilistic model
- structure learning
- approximate inference
- gene regulation
- markov networks
- binding sites
- bayesian networks
- regulatory networks
- gene expression
- human genome
- conditional independence
- microarray
- component analysis
- biological processes
- dna sequences
- saccharomyces cerevisiae
- computational biology
- systems biology
- motif discovery
- single nucleotide polymorphisms
- co occurrence