Alignment-free estimation of sequence conservation for identifying functional sites using protein sequence embeddings.
Wayland YeungZhongliang ZhouSheng LiNatarajan KannanPublished in: Briefings Bioinform. (2023)
Keyphrases
- protein sequences
- sequence alignment
- multiple alignment
- multiple sequence alignment
- multiple sequence alignments
- psi blast
- rna sequences
- sequence analysis
- biological sequences
- amino acids
- computational biology
- secondary structure
- solvent accessibility
- sequence databases
- protein structure
- protein structural
- protein classification
- amino acid sequences
- genome sequences
- protein function
- remote homology detection
- protein structure prediction
- protein folding
- coarse grained
- protein structure and function
- computational approaches
- protein secondary structure
- vector space
- pairwise
- amino acid composition
- machine learning