Statistical Metamodeling and Sequential Design of Computer Experiments to Model Glyco-Altered Gating of Sodium Channels in Cardiac Myocytes.
Dongping DuHui YangAndrew R. EdnieEric S. BennettPublished in: IEEE J. Biomed. Health Informatics (2016)
Keyphrases
- metamodel
- high level
- prior knowledge
- conceptual framework
- mathematical model
- computational model
- objective function
- conceptual model
- theoretical framework
- management system
- probabilistic model
- design process
- parameter estimation
- statistical models
- software architecture
- cost function
- data model
- subject specific
- design rationale