New Method for the Assessment of All Drug-Like Pockets Across a Structural Genome.
George NicolaColin A. SmithRuben AbagyanPublished in: J. Comput. Biol. (2008)
Keyphrases
- high accuracy
- pairwise
- prior knowledge
- cost function
- experimental evaluation
- computational cost
- detection method
- image registration
- optimization method
- high precision
- segmentation method
- synthetic data
- optimization algorithm
- segmentation algorithm
- theoretical analysis
- input data
- genetic algorithm
- support vector machine
- classification accuracy
- dynamic programming
- evolutionary algorithm
- preprocessing