Designing Template-Free Predictor for Targeting Protein-Ligand Binding Sites with Classifier Ensemble and Spatial Clustering.
Dong-Jun YuJun HuJing YangHong-Bin ShenJinhui TangJing-Yu YangPublished in: IEEE ACM Trans. Comput. Biol. Bioinform. (2013)
Keyphrases
- binding sites
- spatial clustering
- classifier ensemble
- protein protein
- virtual screening
- dna binding
- gene expression
- protein protein interactions
- sequence data
- protein interaction
- dna sequences
- regulatory elements
- spatial data
- transcription factors
- clustering method
- computational methods
- transcription factor binding sites
- predicting protein
- protein sequences
- spatial objects
- knowledge discovery
- statistical significance
- ensemble methods
- protein structure
- interaction networks
- high throughput
- base classifiers
- drug design
- data mining
- clustering algorithm
- biological data
- information retrieval