Advanced Protein Alignments Based on Sequence, Structure and Hydropathy Profiles; The Paradigm of the Viral Polymerase Enzyme.
Dimitrios VlachakisAlexandros ArmaosSophia KossidaPublished in: Math. Comput. Sci. (2017)
Keyphrases
- multiple sequence alignments
- sequence alignment
- amino acids
- tertiary structure
- protein sequences
- sequence similarity
- multiple sequence alignment
- psi blast
- pairwise
- protein structural
- contact map
- sequence analysis
- global alignment
- machine learning
- molecular structures
- amino acid sequences
- drug discovery
- protein folding
- computational methods
- svm classifier
- neural network
- protein families
- secondary structure
- computational biology
- user profiles
- active learning
- feature selection
- computer vision
- secondary structure of proteins