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An Integrated Disease/Pharmacokinetic/Pharmacodynamic Model Suggests Improved Interleukin-21 Regimens Validated Prospectively for Mouse Solid Cancers.

Moran ElishmereniYuri KheifetzHenrik SøndergaardRune Viig OvergaardZvia Agur
Published in: PLoS Comput. Biol. (2011)
Keyphrases
  • computational model
  • data sets
  • prior knowledge
  • cost function
  • probabilistic model
  • management system
  • theoretical framework
  • statistical model
  • three dimensional
  • multiscale
  • mathematical model