RDscan: A New Method for Improving Germline and Somatic Variant Calling Based on Read Depth Distribution.
Sunho LeeSeokchol HongJonathan WooJae-hak LeeKyunghee KimLucia KimKunsoo ParkJongsun JungPublished in: J. Comput. Biol. (2022)
Keyphrases
- high precision
- computational cost
- neural network
- segmentation method
- dynamic programming
- detection method
- fully automatic
- experimental evaluation
- depth estimation
- gaussian distribution
- error rate
- high accuracy
- classification accuracy
- significant improvement
- computational complexity
- feature set
- theoretical analysis
- k means
- preprocessing
- optimization method
- depth information
- image processing
- normal distribution
- data sets