Evolution Escapes Rugged Fitness Landscapes by Gene Or Genome Doubling: the Blessing of Higher Dimensionality.
Richard GordonPublished in: Comput. Chem. (1994)
Keyphrases
- genome rearrangements
- evolutionary history
- sequenced genomes
- horizontal gene transfer
- fitness landscape
- escherichia coli
- evolution process
- genomic sequences
- natural selection
- evolutionary process
- phylogenetic analysis
- genetic algorithm
- regulatory networks
- evolutionary algorithm
- comparative genomics
- high dimensional
- sequence data
- microarray
- cis regulatory
- gene expression data
- genome scale
- high dimensionality
- genetic programming
- dimensionality reduction
- feature space
- human genome
- gene expression
- metabolic pathways
- gene sets
- nucleotide sequences
- microarray expression data
- coding regions
- artificial life
- population size
- phylogenetic trees
- high throughput sequencing
- gene selection
- fitness function