Prediction of synergistic anti-cancer drug combinations based on drug target network and drug induced gene expression profiles.
Xiangyi LiYingjie XuHui CuiTao HuangDisong WangBaofeng LianWei LiGuangrong QinLanming ChenLu XiePublished in: Artif. Intell. Medicine (2017)
Keyphrases
- gene expression profiles
- microarray
- gene expression
- gene selection
- cancer classification
- gene networks
- drug discovery
- gene expression data
- microarray data
- tumor classification
- dna microarray
- cancer diagnosis
- network structure
- yeast cell cycle
- gene expression datasets
- experimental conditions
- gene expression patterns
- protein function
- network model
- high throughput
- machine learning
- clustering analysis
- training data
- feature selection