Binding Site Prediction for Protein-Protein Interactions and Novel Motif Discovery using Re-occurring Polypeptide Sequences.
Adam Amos-BinksCatalin PatuleaSylvain PitreAndrew SchoenrockYuan GuiJames R. GreenAshkan GolshaniFrank K. H. A. DehnePublished in: BMC Bioinform. (2011)
Keyphrases
- binding sites
- protein interaction
- motif discovery
- biological sequences
- protein protein
- sequence alignment
- sequence analysis
- protein sequences
- gene expression
- sequence data
- transcription factor binding sites
- dna sequences
- protein protein interactions
- transcription factors
- biological processes
- statistical significance
- protein function
- amino acid sequences
- dna binding
- biological data
- protein complexes
- protein structure prediction
- regulatory networks
- protein interaction networks
- sequence databases
- computational biology
- microarray data
- biological networks
- microarray
- protein structure
- amino acids
- high throughput
- high precision
- multiobjective optimization
- association rules
- machine learning