Identifiability methods for biological systems: Determining subsets of parameters through sensitivity analysis, penalty-based optimisation, profile likelihood and LASSO model reduction.
Michael BinnsAlessandro UsaiConstantinos TheodoropoulosPublished in: Comput. Chem. Eng. (2024)
Keyphrases
- sensitivity analysis
- biological systems
- computational model
- influence diagrams
- mathematical model
- variational inequalities
- maximum likelihood
- managerial insights
- mathematical models
- experimental data
- computational models
- linear regression
- biologically inspired
- regression model
- objective function
- feature selection
- machine learning