Discovery of potent IRAK-4 inhibitors as potential anti-inflammatory and anticancer agents using structure-based exploration of IRAK-4 pharmacophoric space coupled with QSAR analyses.
Mohammad A. KhanfarSaja AlQtaishatPublished in: Comput. Biol. Chem. (2019)
Keyphrases
- multi agent
- multi agent systems
- multiagent systems
- discovery process
- space time
- autonomous agents
- structural properties
- data mining
- knowledge discovery
- intelligent agents
- tree structure
- action selection
- artificial agents
- learning agents
- multiple agents
- decision theoretic
- agent model
- software agents
- hierarchical structure
- resource allocation
- dynamic environments
- low dimensional
- cooperative