Sequence Based Prediction of Protein Mutant Stability and Discrimination of Thermophilic Proteins.
M. Michael GromihaLiang-Tsung HuangLien Fu LaiPublished in: PRIB (2008)
Keyphrases
- tertiary structure
- subcellular localization
- amino acids
- protein tertiary structure
- amino acid sequences
- contact map
- protein secondary structure
- amino acid residues
- protein secondary structure prediction
- protein structure
- protein structure prediction
- secondary structure
- protein sequences
- sequence similarity
- protein function
- contact maps
- multiple sequence alignments
- predicting protein
- psi blast
- drug design
- disordered regions
- sequence analysis
- protein structural
- protein interaction
- secondary structure of proteins
- protein homology
- protein function prediction
- physicochemical properties
- protein chains
- sequence alignment
- experimentally determined
- sequence databases
- protein families
- protein classification
- protein structure alignment
- computational methods
- multiple sequence alignment
- protein protein interactions
- protein folding
- molecular biology
- protein interaction data
- dna binding
- genomic sequences
- physico chemical
- protein complexes
- amino acid composition
- protein protein
- phylogenetic trees
- protein protein interaction networks
- cellular processes
- computational biology
- remote homology detection
- feature ranking
- drug discovery