High Resolution Genome Wide Binding Event Finding and Motif Discovery Reveals Transcription Factor Spatial Binding Constraints.
Yuchun GuoShaun MahonyDavid K. GiffordPublished in: PLoS Comput. Biol. (2012)
Keyphrases
- dna binding
- genome wide
- transcription factors
- motif discovery
- high throughput
- chip seq
- binding sites
- transcription factor binding sites
- dna sequences
- microarray
- gene regulation
- component analysis
- statistical significance
- regulatory networks
- pattern discovery
- human genome
- data mining tasks
- gene expression
- co occurrence
- biological sequences
- systems biology
- sequence data
- biological processes
- data mining
- highly correlated
- computational biology
- pairwise