Sparse nonnegative matrix factorization for protein sequence motif discovery.
Wooyoung KimBernard ChenJingu KimYi PanHaesun ParkPublished in: Expert Syst. Appl. (2011)
Keyphrases
- nonnegative matrix factorization
- protein sequences
- motif discovery
- biological sequences
- computational biology
- sequence analysis
- sequence databases
- motif finding
- negative matrix factorization
- matrix factorization
- least squares
- molecular biology
- sparse representation
- protein structure
- amino acids
- secondary structure
- spectral clustering
- principal component analysis
- objective function
- pattern discovery
- data mining tasks
- dna sequences
- multiobjective optimization
- data mining
- binding sites
- document clustering
- sequential patterns
- feature extraction