A novel non-parametric method for uncertainty evaluation of correlation-based molecular signatures: its application on PAM50 algorithm.
Cristóbal FresnoGermán GonzálezGabriela Alejandra MerinoAna Georgina FlesiaOsvaldo L. PodhajcerAndrea S. LleraElmer Andrés FernándezPublished in: Bioinform. (2017)
Keyphrases
- high accuracy
- improved algorithm
- computational complexity
- dynamic programming
- cost function
- significant improvement
- detection method
- preprocessing
- theoretical analysis
- recognition algorithm
- experimental study
- clustering method
- single pass
- detection algorithm
- high efficiency
- experimental evaluation
- synthetic and real images
- objective function
- computational cost
- input data
- matching algorithm
- segmentation algorithm
- mathematical model
- optimal solution
- optimization method
- estimation algorithm
- optimization algorithm
- classification algorithm
- computational efficiency
- computationally efficient
- reconstruction method
- k means
- energy function
- tree structure
- support vector machine svm
- classification method
- evaluation method
- similarity measure
- convergence rate
- search space
- selection algorithm
- probabilistic model
- cross correlation
- learning algorithm
- bayesian framework
- noisy data
- simulated annealing
- support vector machine
- np hard
- evaluation model
- decomposition method
- kernel density estimation