DNA methylation-based classifier and gene expression signatures detect BRCAness in osteosarcoma.
Maxim BarenboimMichal KovácBaptiste AmelineDavid T. W. JonesOlaf WittStefan BielackStefan BurdachDaniel BaumhoerMichaela NathrathPublished in: PLoS Comput. Biol. (2021)
Keyphrases
- gene expression
- microarray technology
- microarray
- gene regulation
- binding sites
- colon cancer
- microarray data
- gene expression data
- gene expression data analysis
- high throughput
- biological processes
- gene expression patterns
- computational methods
- dna binding
- functional genomics
- biological networks
- gene expression profiles
- decision trees
- gene expression analysis
- dna microarray
- cancer diagnosis
- feature space
- feature selection
- high dimensional data
- support vector machine
- drosophila melanogaster
- gene interactions
- regulatory networks
- microarray datasets
- transcription factors
- dna sequences
- high dimensionality
- co occurrence
- analysis of gene expression