Prediction of conformational epitopes with the use of a knowledge-based energy function and geometrically related neighboring residue characteristics.
Ying-Tsang LoTun-Wen PaiWei-Kuo WuHao-Teng ChangPublished in: BMC Bioinform. (2013)
Keyphrases
- energy function
- graph cuts
- energy minimization
- markov random field
- global minimum
- shape model
- image segmentation
- image intensity
- problems in computer vision
- hopfield neural network
- level set
- belief propagation
- segmentation method
- regularization term
- protein structure prediction
- regularization framework
- contact map
- neural network
- binding peptides
- reconstruction process
- mrf model
- higher order
- artificial neural networks
- objective function
- genetic algorithm