Thermal Stabilization of Dihydrofolate Reductase Using Monte Carlo Unfolding Simulations and Its Functional Consequences.
Jian TianJaie C. WoodardAnna WhitneyEugene I. ShakhnovichPublished in: PLoS Comput. Biol. (2015)
Keyphrases
- monte carlo
- simulation study
- monte carlo simulation
- importance sampling
- markov chain
- infrared
- monte carlo methods
- particle filter
- markovian decision
- adaptive sampling
- stochastic approximation
- temporal difference
- monte carlo tree search
- monte carlo method
- game tree search
- genetic algorithm
- point processes
- variance reduction
- optimal strategy
- optimal solution
- objective function